MMV674850


Catalog No. Size PriceQuantity
M33573-C Contact sales@xcessbio.com for quotation $100

Description

MMV674850 is a novel inhibitor of Plasmodium falciparum gametocytes. MMV674850 is potent against asexual stage parasites at 2.7 and 4.5 nM and preferentially targets early-stage gametocytes (early-stage gametocyte: IC50 4.5 ± 3.6 nM; late-stage gametocyte: IC50 28.7 ± 0.2 nM).

Product information

CAS Number: 1820874-51-8

Molecular Weight: 452.55

Formula: C23H20N2O4S2

Chemical Name: 5-[3-(cyclopropanesulfonyl)phenyl]-3-(4-methanesulfonylphenyl)pyrazolo[1, 5-a]pyridine

Smiles: CS(=O)(=O)C1C=CC(=CC=1)C1C=NN2C=CC(=CC2=1)C1=CC(=CC=C1)S(=O)(=O)C1CC1

InChiKey: BQDDSWFSIPPWHN-UHFFFAOYSA-N

InChi: InChI=1S/C23H20N2O4S2/c1-30(26,27)19-7-5-16(6-8-19)22-15-24-25-12-11-18(14-23(22)25)17-3-2-4-21(13-17)31(28,29)20-9-10-20/h2-8,11-15,20H,9-10H2,1H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: To be determined

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Niemand J, et al. Chemogenomic Fingerprints Associated with Stage-Specific Gametocytocidal Compound Action against Human Malaria Parasites. ACS Infect Dis. 2021 Oct 8;7(10):2904-2916.

Products are for research use only. Not for human use.

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