Ac-IETD-AFC (trifluoroacetate salt)


Catalog No. Size PriceQuantity
M33639-C Contact sales@xcessbio.com for quotation $100

Description

Navitoclax-d8 is the deuterium labeled Navitoclax. Navitoclax (ABT-263) is a potent and orally active Bcl-2 family protein inhibitor that binds to multiple anti-apoptotic Bcl-2 family proteins, such as Bcl-xL, Bcl-2 and Bcl-w, with a Ki of less than 1 nM.

Product information

Molecular Weight: 843.68

Formula: C33H39F6N5O14

Smiles: CC(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(O)=O)C(=O)NC([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)NC1=CC2OC(=O)C=C(C=2C=C1)C(F)(F)F.OC(=O)C(F)(F)F

InChiKey: YWNQGRLHYRWGIP-FKXNOZCSSA-N

InChi: InChI=1S/C31H38F3N5O12.C2HF3O2/c1-5-13(2)25(35-15(4)41)29(49)37-19(8-9-22(42)43)27(47)39-26(14(3)40)30(50)38-20(12-23(44)45)28(48)36-16-6-7-17-18(31(32,33)34)11-24(46)51-21(17)10-16;3-2(4,5)1(6)7/h6-7,10-11,13-14,19-20,25-26,40H,5,8-9,12H2,1-4H3,(H,35,41)(H,36,48)(H,37,49)(H,38,50)(H,39,47)(H,42,43)(H,44,45);(H,6,7)/t13-,14+,19-,20-,25-,26?;/m0./s1

Technical Data

Appearance: Solid Power

Purity: ≥95% (or refer to the Certificate of Analysis)

Solubility: To be determined

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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