STAT3-IN-7

STAT3-IN-7, an aryl sulfonamido azetidine compound, is an orally active STAT3 inhibitor. STAT3-IN-7 has anticancer activities (WO2021016333A1, H182).

Product information

CAS Number: 2237955-91-6

Molecular Weight: 647.62

Formula: C30H26F5N5O4S

Smiles: O=S(=O)(C1C(F)=C(F)C(F)=C(F)C=1F)N1CC[C@@H]1C(=O)N(CC1=CC=C(C=N1)C1CCCCC1)C1=CC=C2C(=C1)N=CNC2=O

InChiKey: XAGZDGDLYLQXQM-JOCHJYFZSA-N

InChi: InChI=1S/C30H26F5N5O4S/c31-23-24(32)26(34)28(27(35)25(23)33)45(43,44)40-11-10-22(40)30(42)39(19-8-9-20-21(12-19)37-15-38-29(20)41)14-18-7-6-17(13-36-18)16-4-2-1-3-5-16/h6-9,12-13,15-16,22H,1-5,10-11,14H2,(H,37,38,41)/t22-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: To be determined

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. James Turkson, et al. Aryl sulfonamides as small molecule stat3 inhibitors. WO2021016333A1.

Products are for research use only. Not for human use.