Description
DprE1-IN-1 is a potent, orally active DprE1 inhibitor with favorable hepatocyte stability, low cytotoxicity and low hERG channel inhibition. DprE1-IN-1 displays potent activity aqainst both drug-susceptible and clinically isolated drug-resistant Tuberculosis strains with MICs<0.1 ug/mL. as well as good intracellular antimycobacterial activity with a 1.29 log1o CFU reduction in macrophages[1]
Product information
CAS Number: 920459-41-2
Molecular Weight: 451.52
Formula: C19H21N3O6S2
Smiles: CCOC(=O)NC(=O)C1C=CSC=1NC(=O)C1C=CC(=CC=1)S(=O)(=O)N1CCCC1
InChiKey: FFUVSZKOCCMGPX-UHFFFAOYSA-N
InChi: InChI=1S/C19H21N3O6S2/c1-2-28-19(25)21-17(24)15-9-12-29-18(15)20-16(23)13-5-7-14(8-6-13)30(26,27)22-10-3-4-11-22/h5-9,12H,2-4,10-11H2,1H3,(H,20,23)(H,21,24,25)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: To be determined
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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