Description
11-beta PGF2α is equipotent to PGF2α in inducing human bronchial smooth muscle contractions and inhibition of adipose differentiation.
Product information
CAS Number: 38432-87-0
Molecular Weight: 354.48
Formula: C20H34O5
Chemical Name: (Z)-7-((1R, 2R, 3S, 5S)-3, 5-dihydroxy-2-((S, E)-3-hydroxyoct-1-en-1-yl)cyclopentyl)hept-5-enoic acid
Smiles: CCCCC[C@H](O)/C=C/[C@@H]1[C@@H](C/C=C\CCCC(O)=O)[C@@H](O)C[C@@H]1O
InChiKey: PXGPLTODNUVGFL-ZWAKLXPCSA-N
InChi: InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-19,21-23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,18-,19-/m0/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: To be determined
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Seibert K, Sheller JR, Roberts LJ 2nd. (5Z,13E)-(15S)-9 alpha,11 beta,15-trihydroxyprosta-5,13-dien-1-oic acid (9 alpha,11 beta-prostaglandin F2): formation and metabolism by human lung and contractile effects on human bronchial smooth muscle. Proc Natl Acad Sci U S A. 1987 Jan;84(1):256-60. doi: 10.1073/pnas.84.1.256. PMID: 3467352; PMCID: PMC304182.
- Hayashi H, Ito S, Tanaka T, Negishi M, Kawabe H, Yokohama H, Watanabe K, Hayaishi O. Determination of 9 alpha, 11 beta-prostaglandin F2 by stereospecific antibody in various rat tissues. Prostaglandins. 1987 Apr;33(4):517-30. doi: 10.1016/0090-6980(87)90275-9. PMID: 3474704.
- Liston TE, Roberts LJ 2nd. Transformation of prostaglandin D2 to 9 alpha, 11 beta-(15S)-trihydroxyprosta-(5Z,13E)-dien-1-oic acid (9 alpha, 11 beta- prostaglandin F2): a unique biologically active prostaglandin produced enzymatically in vivo in humans. Proc Natl Acad Sci U S A. 1985 Sep;82(18):6030-4. doi: 10.1073/pnas.82.18.6030. PMID: 3862115; PMCID: PMC390693.
Products are for research use only. Not for human use.
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