Description
11β-Hydroxyetiocholanolone is a metabolite of hydrocortisone. Fecal levels of 11β-hydroxyetiocholanolone are increased in response to environmental stress in giraffes (G. camelopardalis) and plains zebras (E. quagga).
Product information
CAS Number: 739-26-4
Molecular Weight: 306.44
Formula: C19H30O3
Chemical Name: (3R, 5R, 8S, 9S, 10S, 11S, 13S, 14S)-3, 11-dihydroxy-10, 13-dimethylhexadecahydro-17H-cyclopenta[a]phenanthren-17-one
Smiles: C[C@]12C[C@H](O)[C@H]3[C@@H](CC[C@@H]4C[C@H](O)CC[C@@]43C)[C@@H]1CCC2=O
InChiKey: PIXFHVWJOVNKQK-DLAZEALESA-N
InChi: InChI=1S/C19H30O3/c1-18-8-7-12(20)9-11(18)3-4-13-14-5-6-16(22)19(14,2)10-15(21)17(13)18/h11-15,17,20-21H,3-10H2,1-2H3/t11-,12-,13+,14+,15+,17-,18+,19+/m1/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: To be determined
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Carrera SC, Sen S, Heistermann M, Lu A, Beehner JC. Low rank and primiparity increase fecal glucocorticoid metabolites across gestation in wild geladas. Gen Comp Endocrinol. 2020 Jul 1;293:113494. doi: 10.1016/j.ygcen.2020.113494. Epub 2020 Apr 22. PMID: 32333913.
- Dalerum F, Ganswindt A, Palme R, Bettega C, Delgado MDM, Dehnhard M, Freire S, González RG, Marcos J, Miranda M, Vázquez VM, Corominas TS, Huerta JT, Zedrosser A, Ordiz A, Penteriani V. Methodological Considerations for Using Fecal Glucocorticoid Metabolite Concentrations as an Indicator of Physiological Stress in the Brown Bear (Ursus arctos). Physiol Biochem Zool. 2020 May/Jun;93(3):227-234. doi: 10.1086/708630. PMID: 32228370.
- van Rooyen D, Yadav R, Scott EE, Swart AC. CYP17A1 exhibits 17αhydroxylase/17,20-lyase activity towards 11β-hydroxyprogesterone and 11-ketoprogesterone metabolites in the C11-oxy backdoor pathway. J Steroid Biochem Mol Biol. 2020 May;199:105614. doi: 10.1016/j.jsbmb.2020.105614. Epub 2020 Jan 30. PMID: 32007561.
Products are for research use only. Not for human use.
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