Thalidomide-5,6-F


Catalog No. Size PriceQuantity
M33892-C Contact sales@xcessbio.com for quotation $100

Description

Thalidomide-5, 6-F is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5, 6-F can be connected to the ligand for protein by a linker to form PROTACs.

Product information

CAS Number: 1496997-41-1

Molecular Weight: 294.21

Formula: C13H8F2N2O4

Smiles: O=C1CCC(C(=O)N1)N1C(=O)C2=CC(F)=C(F)C=C2C1=O

InChiKey: AGHXYRKTAZEQQW-UHFFFAOYSA-N

InChi: InChI=1S/C13H8F2N2O4/c14-7-3-5-6(4-8(7)15)13(21)17(12(5)20)9-1-2-10(18)16-11(9)19/h3-4,9H,1-2H2,(H,16,18,19)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: To be determined

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Liu K, et al. Design and biological characterization of hybrid compounds of curcumin and thalidomide for multiple myeloma. Org Biomol Chem. 2013;11(29):4757-4763.

Products are for research use only. Not for human use.

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