Description
3, 6-Dihydroxyflavone is an anti-cancer agent. 3, 6-Dihydroxyflavone dose- and time-dependently decreases cell viability and induces apoptosis by activating caspase cascade, cleaving poly (ADP-ribose) polymerase (PARP). 3, 6-Dihydroxyflavone increases intracellular oxidative stress and lipid peroxidation.
Product information
CAS Number: 108238-41-1
Molecular Weight: 254.24
Formula: C15H10O4
Smiles: OC1C(=O)C2C=C(O)C=CC=2OC=1C1C=CC=CC=1
InChiKey: XHLOLFKZCUCROE-UHFFFAOYSA-N
InChi: InChI=1S/C15H10O4/c16-10-6-7-12-11(8-10)13(17)14(18)15(19-12)9-4-2-1-3-5-9/h1-8,16,18H
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: To be determined
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Chang H, et al. 3,6-Dihydroxyflavone induces apoptosis in leukemia HL-60 cell via reactive oxygen species-mediated p38 MAPK/JNK pathway. Eur J Pharmacol. 2010;648(1-3):31-38.
Products are for research use only. Not for human use.
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