Tau-aggregation-IN-1


Catalog No. Size PriceQuantity
M33999-C Contact sales@xcessbio.com for quotation $100

Description

Tau-aggregation-IN-1 (Compound D-519) is a tau441 protein aggregation inhibitor with an IC50 of 21 µM. Tau-aggregation-IN-1 is also a dopamine D2 and D3 receptor agonist[1].

Product information

CAS Number: 1619269-19-0

Molecular Weight: 507.69

Formula: C28H37N5O2S

Smiles: CCCN(CCN1CCN(CC1)C1C=CC(=CC=1)C1=CC(O)=C(O)C=C1)[C@H]1CC2SC(N)=NC=2CC1

InChiKey: IGXNQKRXZZPFHF-HSZRJFAPSA-N

InChi: InChI=1S/C28H37N5O2S/c1-2-11-32(23-8-9-24-27(19-23)36-28(29)30-24)15-12-31-13-16-33(17-14-31)22-6-3-20(4-7-22)21-5-10-25(34)26(35)18-21/h3-7,10,18,23,34-35H,2,8-9,11-17,19H2,1H3,(H2,29,30)/t23-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: To be determined

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Iva Ziu, et al. The multifunctional dopamine D2/D3 receptor agonists also possess inhibitory activity against the full-length tau441 protein aggregation. Bioorg Med Chem. 2020 Sep 15;28(18):115667.

Products are for research use only. Not for human use.

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