PDE9-IN-(S)-C33

PDE9-IN-(S)-C33 is a potent and selective inhibitor of phosphodiesterase-9 (PDE9).

Product information

CAS Number: 2066488-39-7

Molecular Weight: 357.84

Formula: C18H20ClN5O

Chemical Name: 6-[[(1S)-1-(4-Chlorophenyl)ethyl]amino]-1-cyclopentyl-1, 5-dihydro-4H-pyrazolo[3, 4-d]pyrimidin-4-one

Smiles: C[C@H](NC1NC(=O)C2C=NN(C3CCCC3)C=2N=1)C1=CC=C(Cl)C=C1

InChiKey: FIUCLBJMUGCQTF-NSHDSACASA-N

InChi: InChI=1S/C18H20ClN5O/c1-11(12-6-8-13(19)9-7-12)21-18-22-16-15(17(25)23-18)10-20-24(16)14-4-2-3-5-14/h6-11,14H,2-5H2,1H3,(H2,21,22,23,25)/t11-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: To be determined

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Huang M, Shao Y, Hou J, Cui W, Liang B, Huang Y, Li Z, Wu Y, Zhu X, Liu P, Wan Y, Ke H, Luo HB. Structural Asymmetry of Phosphodiesterase-9A and a Unique Pocket for Selective Binding of a Potent Enantiomeric Inhibitor. Mol Pharmacol. 2015 Nov;88(5):836-45. doi: 10.1124/mol.115.099747. Epub 2015 Aug 27. PubMed PMID: 26316540; PubMed Central PMCID: PMC4613944.

Products are for research use only. Not for human use.