Description
ICI-D 8731 (compound 5g) is a angiotensin II receptor antagonist with the IC50 of 0.031 μM. ICI-D 8731 shows a rapid and sustained lowering of blood pressure in a renal hypertensive rat model.
Product information
CAS Number: 135015-84-8
Molecular Weight: 443.93
Formula: C25H22ClN5O
Smiles: Cl.CCC1=CC(OCC2C=CC(=CC=2)C2=CC=CC=C2C2NN=NN=2)=C2C=CC=CC2=N1
InChiKey: UDVVSNKCOWXHSG-UHFFFAOYSA-N
InChi: InChI=1S/C25H21N5O.ClH/c1-2-19-15-24(22-9-5-6-10-23(22)26-19)31-16-17-11-13-18(14-12-17)20-7-3-4-8-21(20)25-27-29-30-28-25;/h3-15H,2,16H2,1H3,(H,27,28,29,30);1H
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: To be determined
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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