Description
BGN3 is a good substrate for the SNAP-tag? and H5 enzymes. The activities of SNAP-tag? and H5 enzymes on BGN3 are reasonable (IC50= 15.6 and 23.5 μM, respectively). BGN3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Product information
CAS Number: 1151762-33-2
Molecular Weight: 296.29
Formula: C13H12N8O
Chemical Name: 6-{[4-(azidomethyl)phenyl]methoxy}-9H-purin-2-amine
Smiles: [N-]=[N+]=NCC1C=CC(COC2N=C(N)N=C3NC=NC=23)=CC=1
InChiKey: DSPWEULBEPDTGO-UHFFFAOYSA-N
InChi: InChI=1S/C13H12N8O/c14-13-19-11-10(16-7-17-11)12(20-13)22-6-9-3-1-8(2-4-9)5-18-21-15/h1-4,7H,5-6H2,(H3,14,16,17,19,20)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 100 mg/mL (337.51 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
Substrate specificity of SNAP-tag? and H5 by competitive inhibition method (IC50) by using SVG as substrate.
Products are for research use only. Not for human use.
Payment & Security
Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.