BGSN3


Catalog No. Size PriceQuantity
M34804-C Contact sales@xcessbio.com for quotation $100

Description

BGSN3 is a good substrate for the SNAP-tag? and H5 enzymes. The activities of SNAP-tag? and H5 enzymes on BGSN3 are reasonable (IC50=17.8 and 10 μM, respectively). BGSN3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Product information

CAS Number: 2996069-91-9

Molecular Weight: 381.39

Formula: C17H19N9O2

Chemical Name: N-[(4-{[(2-amino-9H-purin-6-yl)oxy]methyl}phenyl)methyl]-4-azidobutanamide

Smiles: [N-]=[N+]=NCCCC(=O)NCC1C=CC(COC2=NC(N)=NC3NC=NC=32)=CC=1

InChiKey: SRNLQFUHOQFWGK-UHFFFAOYSA-N

InChi: InChI=1S/C17H19N9O2/c18-17-24-15-14(21-10-22-15)16(25-17)28-9-12-5-3-11(4-6-12)8-20-13(27)2-1-7-23-26-19/h3-6,10H,1-2,7-9H2,(H,20,27)(H3,18,21,22,24,25)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 100 mg/mL (262.20 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

SNAP-tag? is a powerful technology for the labelling of protein/enzymes by using benzyl-guanine (BG) derivatives as substrates. BGSN3 proved to be a good substrate for the direct immobilisation of these tags (SNAP-tag? and its relative thermo stable version, SsOGT-H5) on solid surfaces.

Products are for research use only. Not for human use.

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