LB-60-OF61 hydrochloride


Catalog No. Size PriceQuantity
M34836-C Contact sales@xcessbio.com for quotation $100

Description

LB-60-OF61 hydrochloride is a potent NAMPT (nicotinamide phosphoribosyltransferase) inhibitor. LB-60-OF61 hydrochloride is a cytotoxic compound with a selectivity towards MYC overexpressing cell lines.

Product information

CAS Number: 742064-38-6

Molecular Weight: 531.05

Formula: C29H31ClN6O2

Chemical Name: 4-{[2-cyano-7-(2-cyclohexylethyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]methoxy}-N-[(pyridin-3-yl)methyl]benzamide hydrochloride

Smiles: Cl.N#CC1=NC2=C(C=C(COC3C=CC(=CC=3)C(=O)NCC3=CN=CC=C3)N2CCC2CCCCC2)C=N1

InChiKey: JKRUYOPCRGPAMD-UHFFFAOYSA-N

InChi: InChI=1S/C29H30N6O2.ClH/c30-16-27-32-19-24-15-25(35(28(24)34-27)14-12-21-5-2-1-3-6-21)20-37-26-10-8-23(9-11-26)29(36)33-18-22-7-4-13-31-17-22;/h4,7-11,13,15,17,19,21H,1-3,5-6,12,14,18,20H2,(H,33,36);1H

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

LB-60-OF61 is potent against HCT116 cells with an IC50 around 30?nM as measured in a 384 well format.

Products are for research use only. Not for human use.

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