NU9056--- KAT5 (Tip60) Histone Acetyltransferase Inhibitor

Catalog No. size PriceQuantity
M60147-2S 2 mg solid $79
M60147-10S 10mg solid $312


NU9056 is a selective KAT5 (Tip60) histone acetyltransferase inhibitor that inhibits protein acetylation in prostate cancer cell lines and blocks DNA damage response. NU9056 also decreases proliferation of LNCaP cells and induces apoptosis via caspase activation.

Product information

CAS Number: 1450644-28-6

Molecular Weight: 232.37

Formula: C6H4N2S4

Chemical Name: 1,2-di(isothiazol-5-yl)disulfane

Smiles: C1C=NSC=1SSC1=CC=NS1


InChi: InChI=1S/C6H4N2S4/c1-3-7-9-5(1)11-12-6-2-4-8-10-6/h1-4H

Technical Data

Appearance: Solid Power.

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO up to 100 mM

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined.

HS Tariff Code: 382200

How to use

In Vitro:

NU9056 was used at 24 µM final concentration in vitro and in cellular assays.


  1. Coffey K, et al. Characterisation of a Tip60 specific inhibitor, NU9056, in prostate cancer. (2012) PLoS One. 7(10):e45539.

Products are for research use only. Not for human use.


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