Atglistatin is a potent and selective adipose triglyceride lipase (ATGL) inhibitor. ATGL is rate limiting in the mobilization of fatty acids from cellular triglyceride stores. This central role in lipolysis marks ATGL as an interesting pharmacological target as deregulated fatty acid metabolism is closely linked to dyslipidemic and metabolic disorders. Atglistatin is selective for ATGL and reduces fatty acid mobilization in vitro and in vivo.
CAS Number: 1469924-27-3
Molecular Weight: 283.37
Chemical Name: 3-(4'-(dimethylamino)biphenyl-3-yl)-1, 1-dimethylurea
Appearance: Solid Power.
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO: 56 mg/mL(197.62 mM).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined.
HS Tariff Code: 382200
- Mayer N, et al. Nat Chem Biol. 2013, 9(12), 785-787.
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