Atglistatin, Adipose Triglyceride Lipase (ATGL) Inhibitor


Catalog No. size PriceQuantity
M60150-2S 2 mg solid $119
M60150-10S 10mg solid $482

Description

Atglistatin is a potent and selective adipose triglyceride lipase (ATGL) inhibitor. ATGL is rate limiting in the mobilization of fatty acids from cellular triglyceride stores. This central role in lipolysis marks ATGL as an interesting pharmacological target as deregulated fatty acid metabolism is closely linked to dyslipidemic and metabolic disorders. Atglistatin is selective for ATGL and reduces fatty acid mobilization in vitro and in vivo.

Product information

CAS Number: 1469924-27-3

Molecular Weight: 283.37

Formula: C17H21N3O

Chemical Name: 3-(4'-(dimethylamino)biphenyl-3-yl)-1, 1-dimethylurea

Smiles: CN(C)C1C=CC(=CC=1)C1=CC(=CC=C1)NC(=O)N(C)C

InChiKey: AWOPBSAJHCUSAS-UHFFFAOYSA-N

InChi: InChI=1S/C17H21N3O/c1-19(2)16-10-8-13(9-11-16)14-6-5-7-15(12-14)18-17(21)20(3)4/h5-12H,1-4H3,(H,18,21)

Technical Data

Appearance: Solid Power.

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO: 56 mg/mL(197.62 mM).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined.

HS Tariff Code: 382200

References:

  1. Mayer N, et al. Nat Chem Biol. 2013, 9(12), 785-787.

Products are for research use only. Not for human use.

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