LY-2886721


Catalog No. size PriceQuantity
M60431-2S 2mg solid $99
M60431-10S 10mg solid $406

Description

LY2886721 is an BACE inhibitor used for the treatment of Alzheimer's Disease. IC50 value: Target: BACE LY2886721 is a novel potent agent that is used to treat Alzheimer’s Disease in preclinical experiments. LY2886721 is under clinical study. A Safety Study of LY2886721 Multiple Doses is performing in Healthy Subjects.

Product information

CAS Number: 1262036-50-9

Molecular Weight: 390.41

Formula: C18H16F2N4O2S

Chemical Name: N-(3-((4aS,7aS)-2-amino-4a,5,7,7a-tetrahydro-4H-furo[3,4-d][1,3]thiazin-7a-yl)-4-fluorophenyl)-5-fluoropicolinamide

Smiles: NC1=N[C@]2(COC[C@H]2CS1)C1=CC(=CC=C1F)NC(=O)C1=CC=C(F)C=N1

InChiKey: NIDRNVHMMDAAIK-YPMLDQLKSA-N

InChi: InChI=1S/C18H16F2N4O2S/c19-11-1-4-15(22-6-11)16(25)23-12-2-3-14(20)13(5-12)18-9-26-7-10(18)8-27-17(21)24-18/h1-6,10H,7-9H2,(H2,21,24)(H,23,25)/t10-,18-/m0/s1

Technical Data

Appearance: Solid Power.

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO: ≥ 42 mg/mL

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined.

HS Tariff Code: 382200

References:

  1. A Safety Study of LY2886721 Multiple Doses in Healthy Subjects

Products are for research use only. Not for human use.

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