LHW090-A7


Catalog No. size PriceQuantity
M6427-2 2mg solid $134
M6427-10 10mg solid $530

Description

LHW090-A7 is a compound developed as an inhibitor of neutral endopeptidase (NEP), an enzyme responsible for the metabolic inactivation of enkephalins.1 Inhibitors of NEP have been shown to increase plasma levels of endogenous atrial natriuretic peptides and, as such, are expected to induce natriuretic and diuretic effects.

Product information

CAS Number: 1308256-94-1

Molecular Weight: 375.85

Formula: C20H22ClNO4

Synonym:

LHW090 A7

LHW090 Analog 7

LHW090A7

Chemical Name: (2S)-3-[4-(3-Chlorophenyl)phenyl]-2-[[(2S)-1-ethoxy-1-oxopropan-2-yl]amino]propanoic acid

Smiles: C[C@H](N[C@@H](CC1C=CC(=CC=1)C1=CC(Cl)=CC=C1)C(O)=O)C(=O)OCC

InChiKey: PWYAUIUPDMSWJH-UGSOOPFHSA-N

InChi: InChI=1S/C20H22ClNO4/c1-3-26-20(25)13(2)22-18(19(23)24)11-14-7-9-15(10-8-14)16-5-4-6-17(21)12-16/h4-10,12-13,18,22H,3,11H2,1-2H3,(H,23,24)/t13-,18-/m0/s1

Technical Data

Appearance: Solid Power.

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined.

HS Tariff Code: 382200

References:

  1. Iwaki, Y. ,Kawanami, T. ,Ksander, G. M., et al. Substituted carbamoylmethylamino acetic acid derivatives as novel NEP inhibitors. (2011).

Products are for research use only. Not for human use.

Payment & Security

American Express Diners Club Discover JCB Mastercard PayPal Venmo Visa

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

Estimate shipping

You may also like

Recently viewed