GSK-3117391

GSK-3117391, also known as GSK3117391A and HDAC-IN-3, is a potent HDAC inhibitor for treating chronic inflammatory disorders.

Product information

CAS Number: 1018673-42-1

Molecular Weight: 403.52

Formula: C22H33N3O4

Synonym:

GSK-3117391A

HDAC-IN-3

HDAC-IN3

HDAC-IN 3

Chemical Name: cyclopentyl(S)-2-cyclohexyl-2-(((6-(3-(hydroxyamino)-3-oxopropyl)pyridin-3-yl)methyl)amino)acetate

Smiles: ONC(=O)CCC1=CC=C(CN[C@@H](C2CCCCC2)C(=O)OC2CCCC2)C=N1

InChiKey: AFDPFLDWOXXHQM-NRFANRHFSA-N

InChi: InChI=1S/C22H33N3O4/c26-20(25-28)13-12-18-11-10-16(14-23-18)15-24-21(17-6-2-1-3-7-17)22(27)29-19-8-4-5-9-19/h10-11,14,17,19,21,24,28H,1-9,12-13,15H2,(H,25,26)/t21-/m0/s1

Technical Data

Appearance: Solid Power.

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined.

HS Tariff Code: 382200

References:

1. Davidson Alan Hornsby, et al. Preparation of amino acid-based hydroxamic acids as histone deacetylase (HDAC) inhibitors. From PCT Int. Appl. (2008), WO 2008040934 A1 20080410.

Products are for research use only. Not for human use.