GSK-3117391

Cas：1018673-42-1

Product Information：

GSK-3117391, also known as GSK3117391A and HDAC-IN-3, is a potent HDAC inhibitor for treating chronic inflammatory disorders.

Chemical Formula: C22H33N3O4

Exact Mass: 403.2471

Molecular Weight: 403.523

Elemental Analysis: C, 65.48; H, 8.24; N, 10.41; O, 15.86

Synonym: 

GSK3117391

GSK-3117391

GSK 3117391

GSK3117391A

GSK-3117391A

GSK 3117391A

HDAC-IN-3

HDAC-IN3

HDAC-IN 3

Chemical Name: 

cyclopentyl(S)-2-cyclohexyl-2-(((6-(3-(hydroxyamino)-3-oxopropyl)pyridin-3-yl)methyl)amino)acetate

InChi Key:

AFDPFLDWOXXHQM-NRFANRHFSA-N

InChi Code:

InChI=1S/C22H33N3O4/c26-20(25-28)13-12-18-11-10-16(14-23-18)15-24-21(17-6-2-1-3-7-17)22(27)29-19-8-4-5-9-19/h10-11,14,17,19,21,24,28H,1-9,12-13,15H2,(H,25,26)/t21-/m0/s1

Smiles Code:

O=C(OC1CCCC1)[C@H](C2CCCCC2)NCC3=CC=C(CCC(NO)=O)N=C3

Technical Data：

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00

References：

1. Davidson Alan Hornsby, et al. Preparation of amino acid-based hydroxamic acids as histone deacetylase (HDAC) inhibitors. From PCT Int. Appl. (2008), WO 2008040934 A1 20080410.

Products are for research use only. Not for human use.