ETH 2120


Catalog No. size PriceQuantity
M6499-2 2mg solid $92
M6499-10 10mg solid $360

Description

Cas:81686-22-8

Product Information:

ETH 2120, also known as Sodium ionophore III, is a ionophore. Ionophore is suitable for the assay of sodium activity in blood, plasma, serum. etc. with a solvent polymeric membrane electrode.

 

Chemical Formula: C34H52N2O4

 

Exact Mass: 552.3927

 

Molecular Weight: 552.8

 

Elemental Analysis: C, 73.87; H, 9.48; N, 5.07; O, 11.58

 

Synonym:

 

ETH 2120

ETH-2120

ETH2120

Sodium ionophore III

 

Chemical Name:

N,N,N′,N′-Tetracyclohexyl-1,2-phenylenedioxydiacetamide

 

InChi Key:

GKRBLFCTFPAHMH-UHFFFAOYSA-N

 

InChi Code: 

InChI=1S/C34H52N2O4/c37-33(35(27-15-5-1-6-16-27)28-17-7-2-8-18-28)25-39-31-23-13-14-24-32(31)40-26-34(38)36(29-19-9-3-10-20-29)30-21-11-4-12-22-30/h13-14,23-24,27-30H,1-12,15-22,25-26H2

 

Smiles Code:

O=C(N(C1CCCCC1)C2CCCCC2)COC3=CC=CC=C3OCC(N(C4CCCCC4)C5CCCCC5)=O

 

 

Technical Data:

 

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

 

In Vitro:

Preincubation of the cells with the Na+ ionophore sodium ionophore III not only stimulated caffeate reduction, but completely abolished ATP synthesis. Addition of sodium ionophore III to cells in the steady state of caffeate reduction immediately dissipated the intracellular ATP level. Lactate-sulfate grown cells are insensitive to the Na+ ionophore, ETH2120. Sodium ionophore III ligand is a very effective receptor for the Eu3+ and Am3+ cations and can be considered as a potential extraction agent for nuclear iste treatment.

 

 

References

 

  1. Imkamp F, et al. Chemiosmotic energy conservation with Na(+) as the coupling ion during hydrogen-dependent caffeate reduction by Acetobacterium woodii. J Bacteriol. 2002 Apr;184(7):1947-51.

 

  1. Wang L, et al. The role of Rnf in ion gradient formation in Desulfovibrio alaskensis. PeerJ. 2016 Apr 14;4:e1919.

 

  1. Makrlík, E, et al. Sodium Ionophore III as Very Effective Receptor for Trivalent Europium and Americium.J Solution Chem (2016) 45: 463.

 

Products are for research use only. Not for human use.

 

Payment & Security

American Express Apple Pay Diners Club Discover Elo Google Pay JCB Mastercard PayPal Shop Pay Venmo Visa

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

Estimate shipping

You may also like

Recently viewed