Description
TRX-818, also known as Foslinanib, CVM-1118, is an orally bioavailable agent with potential antineoplastic and anti-vasculogenic mimicry (VM) activities. Although the exact multiple mechanisms of action through which this agent exerts its effects have yet to be fully elucidated, TRX-818, upon oral administration appears to induce cancer cell apoptosis and inhibits cancer cell proliferation. This agent also prevents tumor cell VM by blocking the formation of vasculogenic-like tubular structures through an as of yet undetermined mechanism of action.
Product information
CAS Number: 1256037-58-7
Molecular Weight: 393.21
Formula: C16H11FNNa2O5P
Synonym:
TRX818 sodium
CVM-1118
Foslinanib sodium
Foslinanib
TRX818
TRX-818
TRX 818
CVM1118
Chemical Name: sodium (2-(3-fluorophenyl)-6-methoxy-4-oxo-1,4-dihydroquinolin-5-yl)phosphonate
Smiles: [Na+].[Na+].COC1=CC=C2NC(=CC(=O)C2=C1P([O-])([O-])=O)C1=CC(F)=CC=C1
InChiKey: ZRPWVAHVWBPHID-UHFFFAOYSA-L
InChi: InChI=1S/C16H13FNO5P.2Na/c1-23-14-6-5-11-15(16(14)24(20,21)22)13(19)8-12(18-11)9-3-2-4-10(17)7-9;;/h2-8H,1H3,(H,18,19)(H2,20,21,22);;/q;2*+1/p-2
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Soluble in DMSO
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined.
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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