TRX-818


Catalog No. size PriceQuantity
M6521-2 2mg solid $93
M6521-10 10mg solid $365

Description

Cas:1256037-58-7

Product Information:

TRX-818, also known as CVM-1118, is an orally bioavailable agent with potential antineoplastic and anti-vasculogenic mimicry (VM) activities. Although the exact multiple mechanisms of action through which this agent exerts its effects have yet to be fully elucidated, TRX-818, upon oral administration appears to induce cancer cell apoptosis and inhibits cancer cell proliferation. This agent also prevents tumor cell VM by blocking the formation of vasculogenic-like tubular structures through an as of yet undetermined mechanism of action.

 

Chemical Formula: C16H11FNNa2O5P

 

Molecular Weight: 393.2177

 

Elemental Analysis: C, 48.87; H, 2.82; F, 4.83; N, 3.56; Na, 11.69; O, 20.34; P, 7.88

 

Synonym:

 

TRX818

TRX-818

TRX 818

TRX818 sodium

CVM1118

CVM1118

CVM-1118

Foslinanib sodium

 

Chemical Name: 

sodium (2-(3-fluorophenyl)-6-methoxy-4-oxo-1,4-dihydroquinolin-5-yl)phosphonate

 

InChi Key: 

ZRPWVAHVWBPHID-UHFFFAOYSA-L

 

InChi Code: 

InChI=1S/C16H13FNO5P.2Na/c1-23-14-6-5-11-15(16(14)24(20,21)22)13(19)8-12(18-11)9-3-2-4-10(17)7-9;;/h2-8H,1H3,(H,18,19)(H2,20,21,22);;/q;2*+1/p-2

 

Smiles Code:

O=C1C=C(C2=CC=CC(F)=C2)NC3=C1C(P([O-])([O-])=O)=C(OC)C=C3.[Na+].[Na+]

 

 

Technical Data:

 

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

 

 

Products are for research use only. Not for human use.

 

 

 

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