DB07268


Catalog No. size PriceQuantity
M6530-2 2mg solid $124
M6530-10 10mg solid $488

Description

DB07268 is a potent and selective JNK1 inhibitor.

Product information

CAS Number: 929007-72-7

Molecular Weight: 321.33

Formula: C17H15N5O2

Synonym:

DB-07268

DB 07268

DB07268

Chemical Name: 2-((2-((3-hydroxyphenyl)amino)pyrimidin-4-yl)amino)benzamide

Smiles: NC(=O)C1=CC=CC=C1NC1=CC=NC(NC2=CC(O)=CC=C2)=N1

InChiKey: QHPKKGUGRGRSGA-UHFFFAOYSA-N

InChi: InChI=1S/C17H15N5O2/c18-16(24)13-6-1-2-7-14(13)21-15-8-9-19-17(22-15)20-11-4-3-5-12(23)10-11/h1-10,23H,(H2,18,24)(H2,19,20,21,22)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : ≥ 32 mg/mL (99.59 mM)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined.

HS Tariff Code: 382200

How to use

In Vitro:

DB07268 (Compound 2b) also inhibits CHK1, PAK4, AKT1, and ERK2 with IC50s of 0.82 μM, 5.5 μM, 15 μM, and 25 μM, respectively.

References:

  1. Liu M, et al. Discovery of a new class of 4-anilinopyrimidines as potent c-Jun N-terminal kinase inhibitors: Synthesis and SAR studies. Bioorg Med Chem Lett. 2007 Feb 1;17(3):668-72.

Products are for research use only. Not for human use.

Payment & Security

PayPal Venmo

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

Estimate shipping

You may also like

Recently viewed