LTI-291


Catalog No. size PriceQuantity
M6538-2 2mg solid $147
M6538-10 10mg solid $592

Description

Cas:1919820-28-2

Product Information:

LTI-291 is a glucocerebrosidase (Gcase) activator for treatment of Parkinson’s disease (PD).

 

Chemical Formula: C20H30N4O2

 

Exact Mass: 358.2369

 

Molecular Weight: 358.486

 

Elemental Analysis: C, 67.01; H, 8.44; N, 15.63; O, 8.93

 

Synonym:

 

LTI-291

LTI 291

LTI291

 

Chemical Name:

5,7-Dimethyl-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (trans-4-pentyloxy-cyclohexyl)-amide

 

InChi Key:

HZILSILAELSWKN-QAQDUYKDSA-N

 

InChi Code: 

InChI=1S/C20H30N4O2/c1-4-5-6-11-26-17-9-7-16(8-10-17)23-20(25)18-13-21-24-15(3)12-14(2)22-19(18)24/h12-13,16-17H,4-11H2,1-3H3,(H,23,25)/t16-,17-

 

Smiles Code:

O=C(C1=C2N=C(C)C=C(C)N2N=C1)N[C@H]3CC[C@H](OCCCCC)CC3

 

 

Technical Data:

 

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

 

 

References:

 

  1. Renato T. Skerlj, et al. Methods of treatment and combination therapies using gcase activator heterobicyclic and related compounds. WO 2017192841 A1.

 

Products are for research use only. Not for human use.

 

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