Catalog No. size PriceQuantity
M6552-2 2mg solid $87
M6552-10 10mg solid $352



Product Information:

SC-79 is an activator of Akt that blocks its membrane translocation while allowing its phosphorylation, in the cytosol, by upstream kinases. SC-79 is a potential treatment for alcohol-induced osteonecrosis of the femoral head. SC-79 injections inhibited alcohol-induced osteonecrosis. Alcohol-induced ONFH is associated with suppression of p-Akt-Ser473 in the Akt/GSK3β/β-catenin signaling pathway in bone mesenchymal stem cells.


Chemical Formula: C17H17ClN2O5


Exact Mass: 364.0826


Molecular Weight: 364.782


Elemental Analysis: C, 55.98; H, 4.70; Cl, 9.72; N, 7.68; O, 21.93





SC 79



Chemical Name:

ethyl 2-amino-6-chloro-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate


InChi Key: 



InChi Code: InChI=1S/C17H17ClN2O5/c1-3-23-16(21)11(8-19)13-10-7-9(18)5-6-12(10)25-15(20)14(13)17(22)24-4-2/h5-7,11,13H,3-4,20H2,1-2H3


Smiles Code:




Technical Data:


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001





  1. Chen YX, Tao SC, Xu ZL, Yin WJ, Zhang YL, Yin JH, Gao YS, Zhang CQ. Novel Akt activator SC-79 is a potential treatment for alcohol-induced osteonecrosis of the femoral head. Oncotarget. 2017 May 9;8(19):31065-31078. doi: 10.18632/oncotarget.16075. PubMed PMID: 28415692; PubMed Central PMCID: PMC5458189.


  1. Yang W, Yang Y, Xia L, Yang Y, Wang F, Song M, Chen X, Liu J, Song Y, Zhao Y, Yang C. MiR-221 Promotes Capan-2 Pancreatic Ductal Adenocarcinoma Cells Proliferation by Targeting PTEN-Akt. Cell Physiol Biochem. 2016;38(6):2366-74. doi: 10.1159/000445589. Epub 2016 May 27. PubMed PMID: 27230035.


  1. Li C, Siragy HM. (Pro)renin receptor regulates autophagy and apoptosis in podocytes exposed to high glucose. Am J Physiol Endocrinol Metab. 2015 Aug 1;309(3):E302-10. doi: 10.1152/ajpendo.00603.2014. Epub 2015 Jun 16. PubMed PMID: 26081285; PubMed Central PMCID: PMC4525115.


Products are for research use only. Not for human use.


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