LY310762


Catalog No. size PriceQuantity
M6571-2 2mg solid $100
M6571-10 10mg solid $401

Description

Cas:192927-92-7

Product Information:

LY310762 is a 5-HT1D antagonist with Ki of 249 nM, having a weaker affinity for 5-HT1B receptor.

 

Chemical Formula: C24H28ClFN2O2

 

Exact Mass: 430.18

 

Molecular Weight: 430.95

 

Elemental Analysis: C, 66.89; H, 6.55; Cl, 8.23; F, 4.41; N, 6.50; O, 7.43

 

Synonym:

 

LY310762

LY 310762

LY-310762

LY310762 HCl

 

Chemical Name: 1-(2-(4-(4-fluorobenzoyl)piperidin-1-yl)ethyl)-3,3-dimethylindolin-2-one hydrochloride

 

InChi Key:

BOCLFQZPFYNVFD-UHFFFAOYSA-N

 

InChi Code: InChI=1S/C24H27FN2O2.ClH/c1-24(2)20-5-3-4-6-21(20)27(23(24)29)16-15-26-13-11-18(12-14-26)22(28)17-7-9-19(25)10-8-17;/h3-10,18H,11-16H2,1-2H3;1H

 

Smiles Code:

O=C1N(CCN2CCC(C(C3=CC=C(F)C=C3)=O)CC2)C4=C(C=CC=C4)C1(C)C.[H]Cl

 

 

Technical Data:

 

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO, not in water

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

 

 

References

 

  1. Pullar IA, et al. The role of the 5-HT1D receptor as a presynaptic autoreceptor in the guinea pig. Eur J Pharmacol, 2004, 493(1-3), 85-93.

 

  1. Choi IS, et al. 5-HT(1B) receptors inhibit glutamate release from primary afferent terminals in rat medullary dorsal horn neurons. Br J Pharmacol, 2012,167(2), 356-367.

 

Products are for research use only. Not for human use.

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