1-Methyl-7-nitroisatoic anhydride


Catalog No. size PriceQuantity
M6601-2 2mg solid $118
M6601-10 10mg solid $488

Description

Cas:73043-80-8

Product Information

1-Methyl-7-nitroisatoic anhydride is a reagent for RNA SHAPE-MaP experiments that enables analysis of RNA secondary structures at single nucleotide resolution in <70 seconds.

 

Chemical Formula: C9H6N2O5

 

Exact Mass: 222.0277

 

Molecular Weight: 222.156 

 

Elemental Analysis: C, 48.66; H, 2.72; N, 12.61; O, 36.01

 

Synonym: 

 

1-methyl-7-nitroisatoic anhydride

73043-80-8

1-methyl-7-nitro-2H-3,1-benzoxazine-2,4(1H)-dione

7-nitro-1-methyl-1H-benzo[d][1,3]oxazine-2,4-dione

1M7

1-methyl-7-nitro-1H-benzo[d][1,3]oxazine-2,4-dione

SCHEMBL13508679

1-Methyl-7-nitroisatoicanhydride

CHEBI:60343

BCP30815

HY-D0913

KS-00001FD7

ZINC39243638

CS-5251

ES-2014

AK340087

SC-65653

1-methyl-7-nitro-3,1-benzoxazine-2,4-dione

Q27127200

1-methyl-7-nitro-2,4-dihydro-1H-3,1-benzoxazine-2,4-dione

1-Methyl-7-nitro-2H-3,1-benzoxazine-2,4(1H)-dione pound>>7-nitro-1-methyl-1H-benzo[d][1,3]oxazine-2,4-dione

 

Chemical Name:

1-Methyl-7-nitro-2H-3,1-benzoxazine-2,4(1H)-dione

 

InChi Key:

MULNCJWAVSDEKJ-UHFFFAOYSA-N

 

InChi Code:    InChI=1S/C9H6N2O5/c1-10-7-4-5(11(14)15)2-3-6(7)8(12)16-9(10)13/h2-4H,1H3

 

Smiles Code:

O=C(O1)N(C)C2=CC([N+]([O-])=O)=CC=C2C1=O

 

 

Technical Data:

 

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

 

 

References

 

  1. Mortimer et al (2007) A fast-acting reagent for accurate analysis of RNA secondary and tertiary structure by SHAPE chemistry. J.Am.Chem.Soc. 129 4144 PMID: 17367143.

 

  1. Turner et al (2013) Safer one-pot synthesis of the 'SHAPE' reagent 1-methyl-7-nitroisatoic anhydride (1m7). RNA 19 1857 PMID: 24141619.

 

  1. Siegfried et al (2014) RNA motif discovery by SHAPE and mutational profiling (SHAPE-MaP). Nat.Methods 11 959 PMID: 25028896.

 

  1. Smola et al (2015) Detection of RNA-Protein interactions in living cells with SHAPE. Biochemistry 54 6867 PMID: 26544910.

 

Products are for research use only. Not for human use.

 

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