7ACC2


Catalog No. size PriceQuantity
M6603-2 2mg solid $113
M6603-10 10mg solid $436

Description

Cas:1472624-85-3

Product Information

7ACC2 is a potent MCT inhibitor. Monocarboxylate transporters (MCTs) catalyze the proton-linked transport of monocarboxylates such as L-lactate, pyruvate, and the ketone bodies across the plasma membrane. There are four isoforms, MCTs 1-4, which are known to perform this function in mammals, each with distinct substrate and inhibitor affinities.

 

Chemical Formula: C18H15NO4

 

Exact Mass: 309.1001

 

Molecular Weight: 309.321

 

Elemental Analysis: C, 69.89; H, 4.89; N, 4.53; O, 20.69

 

Synonym: 

 

7ACC2

7 ACC2

7-ACC2

 

Chemical Name:  

7-(benzyl(methyl)amino)-2-oxo-2H-chromene-3-carboxylic acid

 

InChi Key:

XTKDQPFUOFAMRL-UHFFFAOYSA-N

 

InChi Code:   InChI=1S/C18H15NO4/c1-19(11-12-5-3-2-4-6-12)14-8-7-13-9-15(17(20)21)18(22)23-16(13)10-14/h2-10H,11H2,1H3,(H,20,21)

 

Smiles Code:

O=C1C(C(O)=O)=CC2=CC=C(N(CC3=CC=CC=C3)C)C=C2O1

 

 

Technical Data:

 

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

 

 

References

 

  1. Draoui N, et al. Synthesis and pharmacological evaluation of carboxycoumarins as a new antitumor treatment targeting lactate transport in cancer cells. Bioorg Med Chem. 2013 Nov 15;21(22):7107-17.

 

Products are for research use only. Not for human use.

 

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