WHI-P258


Catalog No. size PriceQuantity
M6613-2 2mg solid $113
M6613-10 10mg solid $441

Description

Cas:21561-09-1

Product Information:

WHI-P258 is a Janus kinase 3 inhibitor. WHI-P131 may provide the basis for the design of new treatment strategies against acute lymphoblastic leukemia, the most common form of childhood cancer.

 

Chemical Formula: C16H15N3O2

 

Exact Mass: 281.1164

 

Molecular Weight: 281.315

 

Elemental Analysis: C, 68.31; H, 5.37; N, 14.94; O, 11.37

 

Synonym: 

 

WHI-P258

WHI-P 258

WHI-P-258

WHIP 258

 

Chemical Name:

6,7-Dimethoxy-N-phenylquinazolin-4-amine

 

InChi Key:

MJKCGAHOCZLYDG-UHFFFAOYSA-N

 

InChi Code: InChI=1S/C16H15N3O2/c1-20-14-8-12-13(9-15(14)21-2)17-10-18-16(12)19-11-6-4-3-5-7-11/h3-10H,1-2H3,(H,17,18,19)

 

Smiles Code:

COC1=CC2=NC=NC(NC3=CC=CC=C3)=C2C=C1OC

 

 

Technical Data:

 

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

 

 

References

 

  1. Sudbeck EA, Liu XP, Narla RK, Mahajan S, Ghosh S, Mao C, Uckun FM. Structure-based design of specific inhibitors of Janus kinase 3 as apoptosis-inducing antileukemic agents. Clin Cancer Res. 1999 Jun;5(6):1569-82. PubMed PMID: 10389946.

 

Products are for research use only. Not for human use.

 

 

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