FIN56 is a specific inducer of ferroptosis.
CAS Number: 1083162-61-1
Molecular Weight: 517.66
Chemical Name: N2,N7-Dicyclohexyl-9-(hydroxyimino)-9H-fluorene-2,7-disulfonamide
Appearance: Solid Power.
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Soluble in DMSO
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined.
HS Tariff Code: 382200
How to use
FIN56 (5 μM) can trigger ferroptosis by inhibition of glutathione peroxidase 4 (GPX4). FIN56 (5 μM, 10 hours) depletes GPX4 protein in HT-1080 cells.
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- Kolasa A. [Epididymis in an experimental model of DHT deficiency: immunolocalization of ERalpha and ERbeta in rat epididymal epithelial cells. In vivo and in vitro studies]. Ann Acad Med Stetin. 2006;52(2):13-21; discussion 21. Polish. PubMed PMID: 17633123.
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