Aurora A Inhibitor I is a selective inhibitor of Aurora kinase A.
Chemical Formula: C31H31ClFN7O2
Exact Mass: 587.2212
Molecular Weight: 588.08
Elemental Analysis: C, 63.31; H, 5.31; Cl, 6.03; F, 3.23; N, 16.67; O, 5.44
TC S 7010
Aurora A Inhibitor I
InChi Code: InChI=1S/C31H31ClFN7O2/c1-2-39-15-17-40(18-16-39)28(41)19-21-7-11-24(12-8-21)36-31-34-20-26(33)29(38-31)35-23-13-9-22(10-14-23)30(42)37-27-6-4-3-5-25(27)32/h3-14,20H,2,15-19H2,1H3,(H,37,42)(H2,34,35,36,38)
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
Aurora A Inhibitor I is exceptionally selective Aurora A inhibitors.
Aurora A Inhibitor I is an useful tool compounds for investigating the cellular role of Aurora A kinases without the complication of also inhibiting Aurora B.
Lee DH, Kim CG, Lim Y, Shin SY. Aurora kinase A inhibitor Aurora A Inhibitor Idemonstrates pro-apoptotic effect through the unfolded protein response pathway in HCT116 colon cancer cells. Oncol Lett. 2017 Dec;14(6):6571-6577. doi: 10.3892/ol.2017.7023. Epub 2017 Sep 22. PubMed PMID: 29163689; PubMed Central PMCID: PMC5686436.
Products are for research use only. Not for human use.
Payment & Security
Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.