Aurora A Inhibitor I

Catalog No. size PriceQuantity
M6681-2 2mg solid $145
M6681-10 10mg solid $603



Product Information

Aurora A Inhibitor I is a selective inhibitor of Aurora kinase A.


Chemical Formula: C31H31ClFN7O2


Exact Mass: 587.2212


Molecular Weight: 588.08 


Elemental Analysis: C, 63.31; H, 5.31; Cl, 6.03; F, 3.23; N, 16.67; O, 5.44




TC-S 7010

TC S 7010


Aurora A Inhibitor I


Chemical Name:



InChi Key:



InChi Code:    InChI=1S/C31H31ClFN7O2/c1-2-39-15-17-40(18-16-39)28(41)19-21-7-11-24(12-8-21)36-31-34-20-26(33)29(38-31)35-23-13-9-22(10-14-23)30(42)37-27-6-4-3-5-25(27)32/h3-14,20H,2,15-19H2,1H3,(H,37,42)(H2,34,35,36,38)


Smiles Code:




Technical Data:


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001


In Vitro

Aurora A Inhibitor I is exceptionally selective Aurora A inhibitors.

Aurora A Inhibitor I is an useful tool compounds for investigating the cellular role of Aurora A kinases without the complication of also inhibiting Aurora B.




  1. Lee DH, Kim CG, Lim Y, Shin SY. Aurora kinase A inhibitor Aurora A Inhibitor Idemonstrates pro-apoptotic effect through the unfolded protein response pathway in HCT116 colon cancer cells. Oncol Lett. 2017 Dec;14(6):6571-6577. doi: 10.3892/ol.2017.7023. Epub 2017 Sep 22. PubMed PMID: 29163689; PubMed Central PMCID: PMC5686436.


Products are for research use only. Not for human use.

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