Catalog No. size PriceQuantity
M6700-2 2mg solid $140
M6700-10 10mg solid $570


WAY262611 HCl is a Wnt pathway agonist acting via inhibition of Dkk1 with no GSK-3.

Product information

CAS Number: 1123231-07-1

Molecular Weight: 391.34

Formula: C20H24Cl2N4


WAY-262611 2HCl

WAY-262611 dihydrochloride

WAY262611 2HCl

WAY 262611 dihydrochloride

WAY-262611 dihydrochloride WAY 262611 dihydrochloride

Chemical Name: (1-(4-(Naphthalen-2-yl)pyrimidin-2-yl)piperidin-4-yl)methanamine Dihydrochloride

Smiles: Cl.Cl.NCC1CCN(CC1)C1=NC(=CC=N1)C1=CC2=CC=CC=C2C=C1


InChi: InChI=1S/C20H22N4.2ClH/c21-14-15-8-11-24(12-9-15)20-22-10-7-19(23-20)18-6-5-16-3-1-2-4-17(16)13-18;;/h1-7,10,13,15H,8-9,11-12,14,21H2;2*1H

Technical Data

Appearance: Solid Power.

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined.

HS Tariff Code: 382200

How to use

In Vitro:

WAY-262611 has the most potent activity in the primary assay, low kinase inhibition potential, and high solubility.

In Vivo:

WAY-262611 has excellent pharmacokinetic properties and shows a dose dependent increase in the trabecular bone formation rate in ovariectomized rats following oral administration. Calvariae from wt mice treated with WAY-262611 shows statistically increased BFR, while similarly treated KO animals are no different from control. This indicates that WAY-262611 is acting via the Wnt β-catenin pathway and most likely through inhibition of Dkk-1.


  1. Polakis P. Wnt signaling and cancer. Genes Dev. 2000 Aug 1;14(15):1837-51. Review. PubMed PMID: 10921899.

Products are for research use only. Not for human use.

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