DL-AP4


Catalog No. size PriceQuantity
M6718-2 2mg solid $98
M6718-10 10mg solid $401

Description

Cas:20263-07-4

Product Information

DL-AP4 is an NMDA glutamate receptor antagonist.

 

Chemical Formula: C4H10NO5P

 

Exact Mass: 183.0297

 

Molecular Weight: 183.0998

 

Elemental Analysis: C, 26.24; H, 5.51; N, 7.65; O, 43.69; P, 16.92

 

Synonym: 

 

AP4

AP 4

AP-4

DL-AP4

 

Chemical Name:  

2-Amino-4-phosphonobutyric acid

 

InChi Key:

DDOQBQRIEWHWBT-UHFFFAOYSA-N

 

InChi Code:   InChI=1S/C4H10NO5P/c5-3(4(6)7)1-2-11(8,9)10/h3H,1-2,5H2,(H,6,7)(H2,8,9,10)

 

Smiles Code:

O=C(O)C(N)CCP(O)(O)=O

 

 

Technical Data:

 

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

 

 

References

 

  1. Rogge DE, Nicklas JY, Haas SA, Reuter DA, Saugel B. Continuous Noninvasive Arterial Pressure Monitoring Using the Vascular Unloading Technique (CNAP System) in Obese Patients During Laparoscopic Bariatric Operations. Anesth Analg. 2018 Feb;126(2):454-463. doi: 10.1213/ANE.0000000000002660. PubMed PMID: 29261549.

 

  1. Hatsugai N, Nakatsuji A, Unten O, Ogasawara K, Kondo M, Nishimura M, Shimada T, Katagiri F, Hara-Nishimura I. Involvement of Adapter Protein Complex 4 in Hypersensitive Cell Death Induced by Avirulent Bacteria. Plant Physiol. 2017 Dec 14. pii: pp.01610.2017. doi: 10.1104/pp.17.01610. [Epub ahead of print] PubMed PMID: 29242374.

 

  1. Ebrahimi-Fakhari D, Cheng C, Dies K, Diplock A, Pier DB, Ryan CS, Lanpher BC, Hirst J, Chung WK, Sahin M, Rosser E, Darras B, Bennett JT; CureSPG47. Clinical and genetic characterization of AP4B1-associated SPG47. Am J Med Genet A. 2018 Feb;176(2):311-318. doi: 10.1002/ajmg.a.38561. Epub 2017 Nov 28. PubMed PMID: 29193663.

 

  1. Mattera R, Park SY, De Pace R, Guardia CM, Bonifacino JS. AP-4 mediates export of ATG9A from the trans-Golgi network to promote autophagosome formation. Proc Natl Acad Sci U S A. 2017 Dec 12;114(50):E10697-E10706. doi: 10.1073/pnas.1717327114. Epub 2017 Nov 27. PubMed PMID: 29180427; PubMed Central PMCID: PMC5740629.

 

  1. Shakeel E, Akhtar S, Khan MKA, Lohani M, Arif JM, Siddiqui MH. Molecular docking analysis of aplysin analogs targeting survivin protein. Bioinformation. 2017 Sep 30;13(9):293-300. doi: 10.6026/97320630013293. eCollection 2017. PubMed PMID: 29081608; PubMed Central PMCID: PMC5651222.

 

Products are for research use only. Not for human use.

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