AZD-5423


Catalog No. size PriceQuantity
M6774-2 2mg solid $146
M6774-10 10mg solid $596

Description

AZD-5423 is a nonsteroidal glucocorticoid by AstraZeneca used to treat respiratory diseases and in particular chronic obstructive pulmonary disease.

Product information

CAS Number: 1034148-04-3

Molecular Weight: 487.45

Formula: C25H21F4N3O3

Synonym:

AZD5423

Chemical Name: 2,2,2-Trifluoro-N-((1R,2S)-1-((1-(4-fluorophenyl)-1H-indazol-5-yl)oxy)-1-(3-methoxyphenyl)-2-propanyl)acetamide

Smiles: C[C@H](NC(=O)C(F)(F)F)[C@H](OC1C=C2C=NN(C3=CC=C(F)C=C3)C2=CC=1)C1=CC(=CC=C1)OC

InChiKey: FCNQMDSJHADDFT-WNSKOXEYSA-N

InChi: InChI=1S/C25H21F4N3O3/c1-15(31-24(33)25(27,28)29)23(16-4-3-5-20(12-16)34-2)35-21-10-11-22-17(13-21)14-30-32(22)19-8-6-18(26)7-9-19/h3-15,23H,1-2H3,(H,31,33)/t15-,23-/m0/s1

Technical Data

Appearance: Solid Power.

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO, not in water

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined.

HS Tariff Code: 382200

References:

  1. Norman P. Crystalline forms of 2,2,2-trifluoro-N-[(1R,2S)-1-{[1-(4-fluorophenyl)-1H-indazol-5-yl]oxy}-1-(3-metho xyphenyl)-2-propanyl]acetamide (AZD-5423). Expert Opin Ther Pat. 2013 Sep;23(9):1239-45. doi: 10.1517/13543776.2013.820706. Epub 2013 Jul 19. PubMed PMID: 23865465.

Products are for research use only. Not for human use.

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