HA-100 dihydrochloride


Catalog No. size PriceQuantity
M6804-2 2mg solid $87
M6804-10 10mg solid $353

Description

Cas:84468-24-6

Product Information

HA-100 dihydrochloride is a protein kinase inhibitor, inhibiting superoxide release from human neutrophils (PMN).

 

Chemical Formula: C13H17Cl2N3O2S

 

Exact Mass: 349.0419

 

Molecular Weight: 350.258

 

Elemental Analysis: C, 44.58; H, 4.89; Cl, 20.24; N, 12.00; O, 9.14; S, 9.15

 

Synonym: 

 

HA-100 dihydrochloride

 

Chemical Name: 

5-Piperazin-1-ylsulfonylisoquinoline;dihydrochloride

 

InChi Key: 

ZKQAPKKKTQCVKG-UHFFFAOYSA-N

 

InChi Code:

InChI=1S/C13H15N3O2S.2ClH/c17-19(18,16-8-6-14-7-9-16)13-3-1-2-11-10-15-5-4-12(11)13;;/h1-5,10,14H,6-9H2;2*1H

 

Smiles Code:

O=S(C1=CC=CC2=C1C=CN=C2)(N3CCNCC3)=O.[H]Cl.[H]Cl

 

Technical Data:

 

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

 

In Vitro:

HA-100 inhibits MLC-kinase and PKC competitively with respect to ATP, and the Ki values are 61 and 6.5 μM, respectively.

 

 

References

 

Hagiwara M, et al. Selective modulation of calcium-dependent myosin phosphorylation by novel protein kinase inhibitors, isoquinolinesulfonamide derivatives. Mol Pharmacol. 1987 Jul;32(1):7-12.

 

Products are for research use only. Not for human use.

Payment & Security

American Express Apple Pay Diners Club Discover Elo Google Pay JCB Mastercard PayPal Shop Pay Venmo Visa

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

Estimate shipping

You may also like

Recently viewed