HA-100 dihydrochloride

Catalog No. size PriceQuantity
M6804-2 2mg solid $87
M6804-10 10mg solid $353


HA-100 dihydrochloride is a protein kinase inhibitor, inhibiting superoxide release from human neutrophils (PMN).

Product information

CAS Number: 84468-24-6

Molecular Weight: 350.26

Formula: C13H17Cl2N3O2S


HA-100 dihydrochloride

Chemical Name: 5-Piperazin-1-ylsulfonylisoquinoline;dihydrochloride

Smiles: Cl.Cl.O=S(=O)(C1=CC=CC2=CN=CC=C21)N1CCNCC1


InChi: InChI=1S/C13H15N3O2S.2ClH/c17-19(18,16-8-6-14-7-9-16)13-3-1-2-11-10-15-5-4-12(11)13;;/h1-5,10,14H,6-9H2;2*1H

Technical Data

Appearance: Solid Power.

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined.

HS Tariff Code: 382200

How to use

In Vitro:

HA-100 inhibits MLC-kinase and PKC competitively with respect to ATP, and the Ki values are 61 and 6.5 μM, respectively.


  1. Hagiwara M, et al. Selective modulation of calcium-dependent myosin phosphorylation by novel protein kinase inhibitors, isoquinolinesulfonamide derivatives. Mol Pharmacol. 1987 Jul;32(1):7-12.

Products are for research use only. Not for human use.

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