HA-100 dihydrochloride


Catalog No. size PriceQuantity
M6804-2 2mg solid $87
M6804-10 10mg solid $353

Description

HA-100 dihydrochloride is a protein kinase inhibitor, inhibiting superoxide release from human neutrophils (PMN).

Product information

CAS Number: 84468-24-6

Molecular Weight: 350.26

Formula: C13H17Cl2N3O2S

Chemical Name: 5-Piperazin-1-ylsulfonylisoquinoline;dihydrochloride

Smiles: Cl.Cl.O=S(=O)(C1=CC=CC2=CN=CC=C21)N1CCNCC1

InChiKey: ZKQAPKKKTQCVKG-UHFFFAOYSA-N

InChi: InChI=1S/C13H15N3O2S.2ClH/c17-19(18,16-8-6-14-7-9-16)13-3-1-2-11-10-15-5-4-12(11)13;;/h1-5,10,14H,6-9H2;2*1H

Technical Data

Appearance: Solid Power.

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined.

HS Tariff Code: 382200

How to use

In Vitro:

HA-100 inhibits MLC-kinase and PKC competitively with respect to ATP, and the Ki values are 61 and 6.5 μM, respectively.

References:

  1. Hagiwara M, et al. Selective modulation of calcium-dependent myosin phosphorylation by novel protein kinase inhibitors, isoquinolinesulfonamide derivatives. Mol Pharmacol. 1987 Jul;32(1):7-12.

Products are for research use only. Not for human use.

Payment & Security

American Express Diners Club Discover JCB Mastercard PayPal Venmo Visa

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

Estimate shipping

You may also like

Recently viewed