O-Desmethyl Midostaurin

Catalog No. size PriceQuantity
M6829-2 2mg solid $658
M6829-10 10mg solid $2,636



Product Information

O-Desmethyl Midostaurin (CGP62221; O-Desmethyl PKC412) is the active metabolite of Midostaurin (HY-10230) via cytochrome P450 liver enzyme metabolism. O-Desmethyl Midostaurin can be used as an indicator for Midostaurin metabolism in vivo[1]. Midostaurin is a multi-targeted protein kinase inhibitor with IC50 ranging from 22-500 nM.





O-Desmethyl PKC412


IC50 & Target: IC50:active metabolite of Midostaurin


Molecular Weight: 556.61


Chemical Formula: C₃₄H₂₈N₄O₄


Smiles Code:




Room temperature in continental US; may vary elsewhere.


Storage Condition:

Please store the product under the recommended conditions in the Certificate of Analysis.





  1. Levis M, et al. Plasma inhibitory activity (PIA): a pharmacodynamic assay reveals insights into the basis for cytotoxic response to FLT3 inhibitors.Blood. 2006 Nov 15;108(10):3477-83.


Products are for research use only. Not for human use.


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