SB-7720770 2HCl

Cas： 607373-46-6

Product Information：

SB-7720770 2HCl is a Rho kinase inhibitor.

Chemical Formula: C15H20Cl2N8O2

Exact Mass: 414.1086

Molecular Weight: 415.27

Elemental Analysis: C, 43.38; H, 4.85; Cl, 17.07; N, 26.98; O, 7.71

Synonym: 

SB-7720770 dihydrochloride

Chemical Name: 4-(7-{[(3S)-3-Amino-1-pyrrolidinyl]carbonyl}-1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-amine dihydrochloride

InChi Key: 

HSROPTGRSYJPJY-JZGIKJSDSA-N

InChi Code: InChI=1S/C15H18N8O2.2ClH/c1-2-23-12-9(15(24)22-4-3-8(16)7-22)5-18-6-10(12)19-14(23)11-13(17)21-25-20-11;;/h5-6,8H,2-4,7,16H2,1H3,(H2,17,21);2*1H/t8-;;/m0../s1

Smiles Code:

NC1=NON=C1C(N2CC)=NC3=C2C(C(N4C[C@@H](N)CC4)=O)=CN=C3.[H]Cl.[H]Cl

Technical Data：

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

References：

1. Battershill JM, Fielder RJ. Mouse-specific carcinogens: an assessment of hazard and significance for validation of short-term carcinogenicity bioassays in transgenic mice. Hum Exp Toxicol. 1998 Apr;17(4):193-205. Review. PubMed PMID: 9617631.

2. Vesselinovitch SD, Rao KV, Mihailovich N. Neoplastic response of mouse tissues during perinatal age periods and its significance in chemical carcinogenesis. Natl Cancer Inst Monogr. 1979 May;(51):239-50. Review. PubMed PMID: 384263.

3. Ledochowski A. Ledakrin--anticancerous medicine 1-nitro-9(3-dimethylaminopropylamino)-acridine -2HCl-H2O. Mater Med Pol. 1976 Jul-Sep;8(3):237-51. Review. PubMed PMID: 796591.

Products are for research use only. Not for human use.