SB-7720770 2HCl

SB-7720770 2HCl is a Rho kinase inhibitor.

Product information

CAS Number: 607373-46-6

Molecular Weight: 415.28

Formula: C15H20Cl2N8O2

Synonym:

SB-7720770 dihydrochloride

Chemical Name: 4-(7-{[(3S)-3-Amino-1-pyrrolidinyl]carbonyl}-1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-amine dihydrochloride

Smiles: Cl.Cl.CCN1C2C(=CN=CC=2C(=O)N2CC[C@H](N)C2)N=C1C1=NON=C1N

InChiKey: HSROPTGRSYJPJY-JZGIKJSDSA-N

InChi: InChI=1S/C15H18N8O2.2ClH/c1-2-23-12-9(15(24)22-4-3-8(16)7-22)5-18-6-10(12)19-14(23)11-13(17)21-25-20-11;;/h5-6,8H,2-4,7,16H2,1H3,(H2,17,21);2*1H/t8-;;/m0../s1

Technical Data

Appearance: Solid Power.

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined.

HS Tariff Code: 382200

References:

1. Battershill JM, Fielder RJ. Mouse-specific carcinogens: an assessment of hazard and significance for validation of short-term carcinogenicity bioassays in transgenic mice. Hum Exp Toxicol. 1998 Apr;17(4):193-205. Review. PubMed PMID: 9617631.
2. Vesselinovitch SD, Rao KV, Mihailovich N. Neoplastic response of mouse tissues during perinatal age periods and its significance in chemical carcinogenesis. Natl Cancer Inst Monogr. 1979 May;(51):239-50. Review. PubMed PMID: 384263.
3. Ledochowski A. Ledakrin--anticancerous medicine 1-nitro-9(3-dimethylaminopropylamino)-acridine -2HCl-H2O. Mater Med Pol. 1976 Jul-Sep;8(3):237-51. Review. PubMed PMID: 796591.

Products are for research use only. Not for human use.