Description
SB-7720770 2HCl is a Rho kinase inhibitor.
Product information
CAS Number: 607373-46-6
Molecular Weight: 415.28
Formula: C15H20Cl2N8O2
Synonym:
SB-7720770 dihydrochloride
Chemical Name: 4-(7-{[(3S)-3-Amino-1-pyrrolidinyl]carbonyl}-1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-amine dihydrochloride
Smiles: Cl.Cl.CCN1C2C(=CN=CC=2C(=O)N2CC[C@H](N)C2)N=C1C1=NON=C1N
InChiKey: HSROPTGRSYJPJY-JZGIKJSDSA-N
InChi: InChI=1S/C15H18N8O2.2ClH/c1-2-23-12-9(15(24)22-4-3-8(16)7-22)5-18-6-10(12)19-14(23)11-13(17)21-25-20-11;;/h5-6,8H,2-4,7,16H2,1H3,(H2,17,21);2*1H/t8-;;/m0../s1
Technical Data
Appearance: Solid Power.
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Soluble in DMSO
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined.
HS Tariff Code: 382200
References:
- Battershill JM, Fielder RJ. Mouse-specific carcinogens: an assessment of hazard and significance for validation of short-term carcinogenicity bioassays in transgenic mice. Hum Exp Toxicol. 1998 Apr;17(4):193-205. Review. PubMed PMID: 9617631.
- Vesselinovitch SD, Rao KV, Mihailovich N. Neoplastic response of mouse tissues during perinatal age periods and its significance in chemical carcinogenesis. Natl Cancer Inst Monogr. 1979 May;(51):239-50. Review. PubMed PMID: 384263.
- Ledochowski A. Ledakrin--anticancerous medicine 1-nitro-9(3-dimethylaminopropylamino)-acridine -2HCl-H2O. Mater Med Pol. 1976 Jul-Sep;8(3):237-51. Review. PubMed PMID: 796591.
Products are for research use only. Not for human use.
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