Hydrochlorothiazide is a thiazide diuretic often used to treat high blood pressure and swelling due to fluid build up. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium.
Chemical Formula: C7H8ClN3O4S2
Exact Mass: 296.96447
Molecular Weight: 297.74
Elemental Analysis: C, 28.24; H, 2.71; Cl, 11.91; N, 14.11; O, 21.49; S, 21.54
Related CAS #: 58-93-5 58-94-5
Chemical Name: 6-chloro-1,1-dioxo-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide
InChi Code: InChI=1S/C7H8ClN3O4S2/c8-4-1-5-7(2-6(4)16(9,12)13)17(14,15)11-3-10-5/h1-2,10-11H,3H2,(H2,9,12,13)
Appearance: White to off-white crystalline powder.
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
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- Machini WB, David-Parra DN, Teixeira MF. Electrochemical investigation of thevoltammetric determination of hydrochlorothiazide using a nickel hydroxidemodified nickel electrode. Mater Sci Eng C Mater Biol Appl. 2015 Dec 1;57:344-8.doi: 10.1016/j.msec.2015.07.035. Epub 2015 Aug 11. PubMed PMID: 26354274.
- Arafa MF, El-Gizawy SA, Osman MA, El Maghraby GM. Sucralose as co-crystalco-former for hydrochlorothiazide: development of oral disintegrating tablets.Drug Dev Ind Pharm. 2015 Dec 7:1-9. [Epub ahead of print] PubMed PMID: 26555927.
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