Pirfenidone D5

Catalog No. size PriceQuantity
M6889-2 2mg solid $250
M6889-10 10mg solid $1,008



Product Information

Pirfenidone D5 (AMR69 D5) is a deuterium labeled Pirfenidone. Pirfenidone is an antifibrotic agent that attenuates CCL2 and CCL12 production in fibrocyte cells. Pirfenidone has growth-inhibitory effect and reduces TGF-β2 protein levels in human glioma cell lines. Pirfenidone also has anti-inflammatory activities.




AMR69 D5


IC50 & Target:


CCL2 and CCL12


Molecular Weight:190.25


Chemical Formula:C₁₂H₆D₅NO


Smiles Code:




Room temperature in continental US; may vary elsewhere.


Storage Condition:

Please store the product under the recommended conditions in the Certificate of Analysis.





  1. Burghardt I, et al. Pirfenidone inhibits TGF-beta expression in malignant glioma cells. Biochem Biophys Res Commun. 2007 Mar 9;354(2):542-7.


  1. Nakazato H, et al. A novel anti-fibrotic agent pirfenidone suppresses tumor necrosis factor-alpha at the translational level. Eur J Pharmacol. 2002 Jun 20;446(1-3):177-85.


  1. Inomata M, et al. Pirfenidone inhibits fibrocyte accumulation in the lungs in bleomycin-induced murine pulmonary fibrosis. Respir Res. 2014 Feb 8;15:16.


Products are for research use only. Not for human use.


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