Catalog No. size PriceQuantity
M6907-2 2mg solid $110
M6907-10 10mg solid $441



Product Information

R-268712 is a specific inhibitor of activin receptor-like kinase 5 (ALK5). It is also an orally active transforming growth factor-β type I receptor inhibitor.


Chemical Formula: C20H18FN5O


Exact Mass: 363.1495


Molecular Weight: 363.39


Elemental Analysis: C, 66.10; H, 4.99; F, 5.23; N, 19.27; O, 4.40


Chemical Name:

2-[4-[2-Fluoro-5-[3-(6-methylpyridine-2-yl)-1H-pyrazol-4-yl] phenyl] pyrazol-1-yl]ethanol


InChi Key:



InChi Code: InChI=1S/C20H18FN5O/c1-13-3-2-4-19(24-13)20-17(11-22-25-20)14-5-6-18(21)16(9-14)15-10-23-26(12-15)7-8-27/h2-6,9-12,27H,7-8H2,1H3,(H,22,25)


Smiles Code:




Technical Data:


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >2 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001





  1. Terashima H, Kato M, Ebisawa M, Kobayashi H, Suzuki K, Nezu Y, Sada T. R-268712, an orally active transforming growth factor-β type I receptor inhibitor, prevents glomerular sclerosis in a Thy1 nephritis model. Eur J Pharmacol. 2014 Jul 5;734:60-6. doi: 10.1016/j.ejphar.2014.03.045. Epub 2014 Apr 12. PubMed PMID: 24726873.


Products are for research use only. Not for human use.


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