Methyl vanillate is isolated from Hovenia dulcis.
CAS Number: 3943-74-6
Molecular Weight: 182.17
Chemical Name: Benzoic acid, 4-hydroxy-3-methoxy-, methyl ester
Appearance: Solid Power.
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Soluble in DMSO
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined.
HS Tariff Code: 382200
How to use
Methyl vanillate (0-100 μM) increases the expression and nuclear translocation of β-catenin in calvarial osteoblasts. Methyl vanillate dose-dependently elevates ALP activity in calvarial osteoblasts.
- Al Bujuq N, Arar S, Khalil R. Synthesis and cytotoxic activity of 4-O-β-D-galactopyranosyl derivatives of phenolic acids esters. Nat Prod Res. 2017 Sep 18:1-7. doi: 10.1080/14786419.2017.1375927. [Epub ahead of print] PubMed PMID: 28920447.
- Lim SJ, Kim M, Randy A, Nam EJ, Nho CW. Effects of Hovenia dulcis Thunb. extract and methyl vanillate on atopic dermatitis-like skin lesions and TNF-α/IFN-γ-induced chemokines production in HaCaT cells. J Pharm Pharmacol. 2016 Nov;68(11):1465-1479. doi: 10.1111/jphp.12640. Epub 2016 Oct 2. PubMed PMID: 27696405.
- Ishimata N, Ito H, Tai A. Structure-activity relationships of vanillic acid ester analogs in inhibitory effect of antigen-mediated degranulation in rat basophilic leukemia RBL-2H3 cells. Bioorg Med Chem Lett. 2016 Aug 1;26(15):3533-6. doi: 10.1016/j.bmcl.2016.06.028. Epub 2016 Jun 11. PubMed PMID: 27324979.
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