Methyl vanillate


Catalog No. size PriceQuantity
M6947-2 2mg solid $78
M6947-10 10mg solid $324

Description

Methyl vanillate is isolated from Hovenia dulcis.

Product information

CAS Number: 3943-74-6

Molecular Weight: 182.17

Formula: C9H10O4

Synonym:

NSC 74385

Methyl vanillate

Chemical Name: Benzoic acid, 4-hydroxy-3-methoxy-, methyl ester

Smiles: COC1=CC(=CC=C1O)C(=O)OC

InChiKey: BVWTXUYLKBHMOX-UHFFFAOYSA-N

InChi: InChI=1S/C9H10O4/c1-12-8-5-6(9(11)13-2)3-4-7(8)10/h3-5,10H,1-2H3

Technical Data

Appearance: Solid Power.

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined.

HS Tariff Code: 382200

How to use

In Vitro:

Methyl vanillate (0-100 μM) increases the expression and nuclear translocation of β-catenin in calvarial osteoblasts. Methyl vanillate dose-dependently elevates ALP activity in calvarial osteoblasts.

References:

  1. Al Bujuq N, Arar S, Khalil R. Synthesis and cytotoxic activity of 4-O-β-D-galactopyranosyl derivatives of phenolic acids esters. Nat Prod Res. 2017 Sep 18:1-7. doi: 10.1080/14786419.2017.1375927. [Epub ahead of print] PubMed PMID: 28920447.
  2. Lim SJ, Kim M, Randy A, Nam EJ, Nho CW. Effects of Hovenia dulcis Thunb. extract and methyl vanillate on atopic dermatitis-like skin lesions and TNF-α/IFN-γ-induced chemokines production in HaCaT cells. J Pharm Pharmacol. 2016 Nov;68(11):1465-1479. doi: 10.1111/jphp.12640. Epub 2016 Oct 2. PubMed PMID: 27696405.
  3. Ishimata N, Ito H, Tai A. Structure-activity relationships of vanillic acid ester analogs in inhibitory effect of antigen-mediated degranulation in rat basophilic leukemia RBL-2H3 cells. Bioorg Med Chem Lett. 2016 Aug 1;26(15):3533-6. doi: 10.1016/j.bmcl.2016.06.028. Epub 2016 Jun 11. PubMed PMID: 27324979.

Products are for research use only. Not for human use.

Payment & Security

PayPal Venmo

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

Estimate shipping

You may also like

Recently viewed