Description
Cas:1198780-38-9
Product Information:
β-catenin/CBP-IN-1 is a potent and selective CBP/β-catenin antagonist, extracted from the patent WO2014092154A1. β-catenin/CBP-IN-1 has the potential for the study of liver fibrosis induced by hepatitis virus.
IC50 & Target: Wnt
Molecular Weight: 658.64
Formula: C₃₃H₃₅N₆O₇P
Smiles:
O=C(N(C([C@H](C)N1CC2=C3N=CC=CC3=CC=C2)N4[C@@H](CC5=CC=C(OP(O)(O)=O)C=C5)C1=O)N(C)CC4=O)NCC6=CC=CC=C6
Shipping:
Room temperature in continental US; may vary elsewhere.
Storage:
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
In Vivo:
β-catenin/CBP-IN-1 (intraperitoneal injection;1mg/kg; 42 days) has a treatment effect on liver fibrosis in hepatic fibrosis Cre/loxP/HCV-MxCreTg mouse model.
References:
-
Takenao Odagami, et al. Prevention or treatment agent for hepatic fibrosis. Patent WO2014092154A1.
Products are for research use only. Not for human use.
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