β-catenin/CBP-IN-1


Catalog No. size PriceQuantity
M6955-2 2mg solid $252
M6955-10 10mg solid $1,008

Description

Cas:1198780-38-9

Product Information:

β-catenin/CBP-IN-1 is a potent and selective CBP/β-catenin antagonist, extracted from the patent WO2014092154A1. β-catenin/CBP-IN-1 has the potential for the study of liver fibrosis induced by hepatitis virus.

 

IC50 & Target: Wnt

 

Molecular Weight: 658.64

 

Formula: C₃₃H₃₅N₆O₇P

 

Smiles:

O=C(N(C([C@H](C)N1CC2=C3N=CC=CC3=CC=C2)N4[C@@H](CC5=CC=C(OP(O)(O)=O)C=C5)C1=O)N(C)CC4=O)NCC6=CC=CC=C6

 

Shipping:

Room temperature in continental US; may vary elsewhere.

 

Storage:

Powder    -20°C  3 years

4°C  2 years

In solvent -80°C  6 months

-20°C  1 month

 

In Vivo:

β-catenin/CBP-IN-1 (intraperitoneal injection;1mg/kg; 42 days) has a treatment effect on liver fibrosis in hepatic fibrosis Cre/loxP/HCV-MxCreTg mouse model.

 

 

References:

 

  1. Takenao Odagami, et al. Prevention or treatment agent for hepatic fibrosis. Patent WO2014092154A1.

 

Products are for research use only. Not for human use.

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