Catalog No. size PriceQuantity
M6956-2 2mg solid $101
M6956-10 10mg solid $406



Product Information:

DK419 is a potent inhibitor of Wnt/β-catenin signaling and colorectal cancer growth. DK419 inhibited Wnt/β-catenin signaling, altered cellular oxygen consumption rate and induced production of pAMPK. DK419 inhibited the growth of CRC tumor cells in vitro, had good plasma exposure when dosed orally, and inhibited the growth of patient derived CRC240 tumor explants in mice dosed orally.


Chemical Formula: C16H8ClF6N3O


Exact Mass: 407.026


Molecular Weight: 407.7004


Elemental Analysis: C, 47.14; H, 1.98; Cl, 8.70; F, 27.96; N, 10.31; O, 3.92


Chemical Name: 



InChi Key:



InChi Code:



Smiles Code:




Technical Data:


Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.03.00





  1. Wang J, Mook RA Jr, Ren XR, Zhang Q, Jing G, Lu M, Spasojevic I, Lyerly HK,Hsu D, Chen W. Identification of DK419, a potent inhibitor of Wnt/β-cateninsignaling and colorectal cancer growth. Bioorg Med Chem. 2018 Sep 17. pii:S0968-0896(18)31138-6. doi: 10.1016/j.bmc.2018.09.016. [Epub ahead of print]PubMed PMID: 30274939.


Products are for research use only. Not for human use.



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