Neurodazine is a neurogenic inducer for converting pluripotent P19 cells into electrophysiologically active neurons.
Chemical Formula: C27H21ClN2O3
Exact Mass: 456.1241
Molecular Weight: 456.92
Elemental Analysis: C, 70.97; H, 4.63; Cl, 7.76; N, 6.13; O, 10.50
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
Halder D, Kim GH, Shin I. Synthetic small molecules that induce neuronal differentiation in neuroblastoma and fibroblast cells. Mol Biosyst. 2015 Oct;11(10):2727-37. doi: 10.1039/c5mb00161g. PubMed PMID: 25872738.
Pérez-Caaveiro C, Pérez Sestelo J, Martínez MM, Sarandeses LA. Triorganoindium reagents in selective palladium-catalyzed cross-coupling with iodoimidazoles: synthesis of neurodazine. J Org Chem. 2014 Oct 17;79(20):9586-93. doi: 10.1021/jo501664p. Epub 2014 Oct 1. PubMed PMID: 25203769.
Kim GH, Halder D, Park J, Namkung W, Shin I. Imidazole-based small molecules that promote neurogenesis in pluripotent cells. Angew Chem Int Ed Engl. 2014 Aug 25;53(35):9271-4. doi: 10.1002/anie.201404871. Epub 2014 Jul 9. PubMed PMID: 25044422.
Products are for research use only. Not for human use.
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