Description
Cas：2204290-85-5
Product Information：
FzM1.8 is an allosteric agonist of the Frizzled receptor FZD4.
Chemical Formula: C18H14N2O4
Exact Mass: 322.0954
Molecular Weight: 322.32
Elemental Analysis: C, 67.08; H, 4.38; N, 8.69; O, 19.85
Chemical Name:
3-Hydroxy-5-(3-(naphthalen-2-yl)ureido)benzoic acid
InChi Key:
XGNNCRZDDAJBFU-UHFFFAOYSA-N
InChi Code:
InChI=1S/C18H14N2O4/c21-16-9-13(17(22)23)8-15(10-16)20-18(24)19-14-6-5-11-3-1-2-4-12(11)7-14/h1-10,21H,(H,22,23)(H2,19,20,24)
Smiles Code:
O=C(O)C1=CC(NC(NC2=CC=C3C=CC=CC3=C2)=O)=CC(O)=C1
Technical Data：
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.03.00
References:
-
Riccio G, Bottone S, La Regina G, Badolati N, Passacantilli S, Rossi GB, Accardo A, Dentice M, Silvestri R, Novellino E, Stornaiuolo M. A Negative Allosteric Modulator of WNT Receptor Frizzled 4 Switches into an Allosteric Agonist. Biochemistry. 2018 Feb 6;57(5):839-851. doi: 10.1021/acs.biochem.7b01087. Epub 2018 Jan 19. PubMed PMID: 29293331.
Products are for research use only. Not for human use.
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