Catalog No. size PriceQuantity
M6958-2 2mg solid $111
M6958-10 10mg solid $452


FzM1.8 is an allosteric agonist of the Frizzled receptor FZD4.

Product information

CAS Number: 2204290-85-5

Molecular Weight: 322.31

Formula: C18H14N2O4

Chemical Name: 3-Hydroxy-5-(3-(naphthalen-2-yl)ureido)benzoic acid

Smiles: OC(=O)C1C=C(O)C=C(C=1)NC(=O)NC1=CC2=CC=CC=C2C=C1


InChi: InChI=1S/C18H14N2O4/c21-16-9-13(17(22)23)8-15(10-16)20-18(24)19-14-6-5-11-3-1-2-4-12(11)7-14/h1-10,21H,(H,22,23)(H2,19,20,24)

Technical Data

Appearance: Solid Power.

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined.

HS Tariff Code: 382200


  1. Riccio G, Bottone S, La Regina G, Badolati N, Passacantilli S, Rossi GB, Accardo A, Dentice M, Silvestri R, Novellino E, Stornaiuolo M. A Negative Allosteric Modulator of WNT Receptor Frizzled 4 Switches into an Allosteric Agonist. Biochemistry. 2018 Feb 6;57(5):839-851. doi: 10.1021/acs.biochem.7b01087. Epub 2018 Jan 19. PubMed PMID: 29293331.

Products are for research use only. Not for human use.

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