Catalog No. size PriceQuantity
M6967-2 2mg solid $132
M6967-10 10mg solid $530


SIS17 is a potent and selective HDAC 11 inhibitor with an IC50 value of 0.83 μM. SIS17, is active in cells and inhibited the demyristoylation of a known HDAC11 substrate, serine hydroxymethyl transferase 2, without inhibiting other HDACs.

Product information

CAS Number: 2374313-54-7

Molecular Weight: 366.60

Formula: C21H38N2OS



SIS 17


Chemical Name: N'-hexadecylthiophene-2-carbohydrazide



InChi: InChI=1S/C21H38N2OS/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18-22-23-21(24)20-17-16-19-25-20/h16-17,19,22H,2-15,18H2,1H3,(H,23,24)

Technical Data

Appearance: Solid Power.

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined.

HS Tariff Code: 382200


  1. Son SI, Cao J, Zhu CL, Miller SP, Lin H. Activity-Guided Design ofHDAC11-Specific Inhibitors. ACS Chem Biol. 2019 Jul 19;14(7):1393-1397. doi:10.1021/acschembio.9b00292. Epub 2019 Jul 2. PubMed PMID: 31264832.

Products are for research use only. Not for human use.

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