CUN25391, a tubulin inhibitor.

Catalog No. size PriceQuantity
M6986-2 2mg solid $80
M6986-10 10mg solid $240


CUN25391, also known as Tubulin inhibitor 6 or iHAP1 (Compound 14b in literature 1) is a tubulin inhibitor and a potent inhibitor of multiple cancer cell lines. CUN25391 inhibits tubulin polymerization with an IC50 of 0.87 μM. CUN25391 has CAS#105925-39-1, no formal name. For the convenience of scientific communication, we named it as CUN25391(combined from Inchi key plus CAS#) according to Hodoodo Chemical Nomenclature (

Product information

CAS Number: 105925-39-1

Molecular Weight: 367.85

Formula: C20H14ClNO2S




CUN 25391


Tubulin inhibitor 6

Chemical Name: (2-chloro-10H-phenothiazin-10-yl)(4-methoxyphenyl)methanone

Smiles: COC1C=CC(=CC=1)C(=O)N1C2=CC(Cl)=CC=C2SC2=CC=CC=C12


InChi: InChI=1S/C20H14ClNO2S/c1-24-15-9-6-13(7-10-15)20(23)22-16-4-2-3-5-18(16)25-19-11-8-14(21)12-17(19)22/h2-12H,1H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Tubulin inhibitor 6 displays submicromolar antiproliferative activity.


  1. Prinz H, et al. N-benzoylated phenoxazines and phenothiazines: synthesis, antiproliferative activity, and inhibition of tubulin polymerization. J Med Chem. 2011 Jun 23;54(12):4247-63.

Products are for research use only. Not for human use.

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