Description
Prothixene, CAS No. 2622-24-4, is a norepinephrine reuptake inhibitor approved for the treatment of attention deficit hyperactivity disorder (ADHD). The brand name is Strattera. The initial therapeutic effects of atomoxetine usually take 2–4 weeks to become apparent. There has been some suggestion that atomoxetine might be a helpful adjunct in people with major depression, especially in cases where ADHD occurs comorbidly to major depression.
Product information
CAS Number: 2622-24-4
Molecular Weight: 283.43
Formula: C18H21NS
Synonym:
2622-24-4
UNII-2HX2OJH78L
2HX2OJH78L
Prothixene [INN]
Prothixenum [INN-Latin]
Protixeno [INN-Spanish]
Prooxin
N,N-dimethyl-3-thioxanthen-9-ylidenepropan-1-amine
10-(3-Dimethylaminopropyliden)thioxanthen
SCHEMBL623020
N,N-Dimethyl-N-(3-(9-thioxanthenyliden)propyl)amin
CHEMBL2107023
DTXSID20180858
API0012360
Q27254766
N,N-Dimethylthioxanthene-delta(sup 9,gamma)-propylamine
Prothixenum
Protixeno
ZINC1997
Chemical Name: 10-(3-Dimethylaminopropyliden)thioxanthen
Smiles: CN(C)CCC=S1C2=CC=CC=C2CC2=CC=CC=C12
InChiKey: MNJIUAXMUGFJJV-UHFFFAOYSA-N
InChi: InChI=1S/C18H21NS/c1-19(2)12-7-13-20-17-10-5-3-8-15(17)14-16-9-4-6-11-18(16)20/h3-6,8-11,13H,7,12,14H2,1-2H3
Technical Data
Appearance: Solid Power.
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Soluble in DMSO
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined.
HS Tariff Code: 382200
References:
- Metys J, Metysová J, Votava Z. Srovnání farmakologických vlastností prothixenu, promethazinu a chlorprothixenu [Comparison of the pharmacological properties of prothixene, promethazine and chlorprothixene]. Cesk Farm. 1966 Dec;15(10):526-30. Czech. PMID: 4382828.
- Jílek JO, Rajsner M, Pomykácek J, Protiva M. Synthetická ataraktika. XII. Prothixen a analogy. Nová synthesa chlorprothixenu [Synthetic ataraxics. XII. Prothixene and analogues. A new synthesis of chlorprothixene]. Cesk Farm. 1965 Aug;14(6):294-303. Czech. PMID: 5852321.
Products are for research use only. Not for human use.
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