Antrodin A

Cas：656830-24-9

Product Information：

Antrodin A, also known as Camphorataanhydride A, is one of the main active ingredients in the solid-state fermented A. camphorata mycelium. It protects the liver from alcohol damage by improving the antioxidant and anti-inflammatory capacity of the liver and maintaining the stability of the intestinal flora.a natural product from mycelium of Antrodia camphorata. Antrodin A alleviates acute alcoholic liver injury and modulates intestinal flora dysbiosis in mice.

Chemical Formula: C19H22O4

Exact Mass: 314.1518

Molecular Weight: 314.381

Elemental Analysis: C, 72.59; H, 7.05; O, 20.36

Synonym:

656830-24-9

Camphorataanhydride A

CHEMBL471117

SCHEMBL1971868

US9115083, Compound 1

BDBM175071

EX-A4258

3-[4-(3-methylbut-2-enoxy)phenyl]-4-(2-methylpropyl)furan-2,5-dione

3-isobutyl-4-[4-(3-methylbut-2-enoxy)phenyl]furan-2,5-dione

3-isobutyl-4-[4-(3-methyl-2-butenyloxy)phenyl] furan-2,5-dione

3-isobutyl-4-[4-(3-methyl-2-butenyloxy)phenyl]furan-2,5-dione

3-Isobutyl-4-(4-((3-methylbut-2-en-1-yl)oxy)phenyl)furan-2,5-dione

Chemical Name: 

2,5-Furandione, 3-(4-((3-methyl-2-butenyl)oxy)phenyl)-4-(2-methylpropyl)-

InChi Key:

ZXIUCXGVUOQMSH-UHFFFAOYSA-N

InChi Code: InChI=1S/C19H22O4/c1-12(2)9-10-22-15-7-5-14(6-8-15)17-16(11-13(3)4)18(20)23-19(17)21/h5-9,13H,10-11H2,1-4H3

Smiles Code:

O=C(C(C1=CC=C(OC/C=C(C)/C)C=C1)=C2CC(C)C)OC2=O

Technical Data：

Appearance: Solid powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: Soluble in DMSO

Shelf Life: >3 years if stored properly

Drug Formulation: This drug may be formulated in DMSO

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

References：

1. Yi ZW, Xia YJ, Liu XF, Wang GQ, Xiong ZQ, Ai LZ. Antrodin A from mycelium of Antrodia camphorata alleviates acute alcoholic liver injury and modulates intestinal flora dysbiosis in mice. J Ethnopharmacol. 2020 May 23;254:112681. doi: 10.1016/j.jep.2020.112681. Epub 2020 Feb 19. PMID: 32087320.

2. Xie JQ, Chen YC, Sun ZH, Liu HX, Li SN, Li HH, Gao XX, Zhang WM. [Sesquiterpenoids of endophytic fungus Cerrena sp. from Pogostemon cablin and their cytotoxic activities]. Zhongguo Zhong Yao Za Zhi. 2017 May;42(9):1693-1698. Chinese. doi: 10.19540/j.cnki.cjcmm.20170224.009. PMID: 29082691.

3. He YC, Lu ZH, Shi P, Hao JC, Zhao ZJ, Xie HT, Mao P, Chen SJ. Anti-herpes simplex virus activities of bioactive extracts from Antrodia camphorata mycelia. Antivir Ther. 2016;21(5):377-83. doi: 10.3851/IMP2988. Epub 2015 Aug 27. PMID: 26313544.

4. Phuong do T, Ma CM, Hattori M, Jin JS. Inhibitory effects of antrodins A-E from Antrodia cinnamomea and their metabolites on hepatitis C virus protease. Phytother Res. 2009 Apr;23(4):582-4. doi: 10.1002/ptr.2657. PMID: 19003946.

Products are for research use only. Not for human use.