BCI inhibitor


Catalog No. size PriceQuantity
M7019-2 2mg solid $120
M7019-10 10mg solid $476

Description

BCI is an allosteric inhibitor of dual specificity phosphatase (DUSP). BCI specifically inhibits DUSP6 and DUSP1 with EC50s of 13.3 and 8.0 μM in cells, respectively

Product information

CAS Number: 1245792-51-1

Molecular Weight: 317.42

Formula: C22H23NO

Synonym:

BCI

-BCI

BCI inhibitor

Chemical Name: BCI inhibitor

Smiles: O=C1C2=CC=CC=C2C(NC2CCCCC2)/C/1=C\C1C=CC=CC=1

InChiKey: XJDKPLZUXCIMIS-HMMYKYKNSA-N

InChi: InChI=1S/C22H23NO/c24-22-19-14-8-7-13-18(19)21(23-17-11-5-2-6-12-17)20(22)15-16-9-3-1-4-10-16/h1,3-4,7-10,13-15,17,21,23H,2,5-6,11-12H2/b20-15+

Technical Data

Appearance: Solid Power.

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined.

HS Tariff Code: 382200

References:

  1. Korotchenko VN, et al. In vivo structure-activity relationship studies support allosteric targeting of a dual specificity phosphatase. Chembiochem. 2014 Jul 7;15(10):1436-45.

Products are for research use only. Not for human use.

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