Diphenylterazine is a bioluminescence agent. Diphenylterazine alone yields very little background, leading to excellent signal-to-background ratios
CAS Number: 344940-63-2
Molecular Weight: 377.44
Chemical Name: 2-benzyl-6,8-diphenylimidazo[1,2-a]pyrazin-3(7H)-one
Appearance: Solid Power.
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Soluble in DMSO
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined.
HS Tariff Code: 382200
How to use
Diphenylterazine elicits minimal cell toxicity at millimolar concentrations.
Diphenylterazine injections into untransfected BALB/c mice do not yield any background emission. The bioluminescence resulting from intraperitoneally injected Diphenylterazine displays extended kinetics. DTZ (0.3 μmol/mouse; i.v.) treatment can track tumor growth in a xenograft NU/J mouse model.
- Yeh HW, Xiong Y, Wu T, et al. ATP-Independent Bioluminescent Reporter Variants To Improve in Vivo Imaging. ACS Chem Biol. 2019;14(5):959-965. doi:10.1021/acschembio.9b00150
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