Diphenylterazine is a bioluminescence agent. Diphenylterazine alone yields very little background, leading to excellent signal-to-background ratios.
Chemical Formula: C25H19N3O
Exact Mass: 377.1528
Molecular Weight: 377.447
Elemental Analysis: C, 79.55; H, 5.07; N, 11.13; O, 4.24
Synonym: Diphenylterazine; DTZ;
InChi Code: InChI=1S/C25H19N3O/c29-25-21(16-18-10-4-1-5-11-18)27-24-23(20-14-8-3-9-15-20)26-22(17-28(24)25)19-12-6-2-7-13-19/h1-15,17,26H,16H2
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >3 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
Diphenylterazine elicits minimal cell toxicity at millimolar concentrations.
Diphenylterazine injections into untransfected BALB/c mice do not yield any background emission. The bioluminescence resulting from intraperitoneally injected Diphenylterazine displays extended kinetics.
DTZ (0.3 μmol/mouse; i.v.) treatment can track tumor growth in a xenograft NU/J mouse model.
Yeh HW, Xiong Y, Wu T, et al. ATP-Independent Bioluminescent Reporter Variants To Improve in Vivo Imaging. ACS Chem Biol. 2019;14(5):959-965. doi:10.1021/acschembio.9b00150
Products are for research use only. Not for human use.
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